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Column Iceland – October 20, 2026

An NMT for health?

If you know what an NMT phone is, or, even more so, if you’ve ever used one, it’s likely that you are formerly young. Slightly less so in Iceland, where well into the 2000s lots of the cool kids still had NMT phones in their jeeps. Your trusty Nokia 3310 could go several days on a charge, but drive away from a town or up a valley and the coverage quickly got spotty. With an NMT, though, you could head up toward the highlands or the upper reaches of a river and never be out of touch.

Clinical Trials – October 20, 2026

ALK’s dust mite allergy tablet succeeds in Chinese Phase 3

Danish allergy company ALK-Abelló reports that its house dust mite tablet Acarizax met the primary objective of a Phase 3 trial in China, with efficacy in line with earlier trials after only 24–28 weeks of treatment. ALK and its partner GenSci plan to file for approval in China in the first half of 2027.

Biotech Business – October 20, 2026

FDA approves Alvotech’s new SIMLANDI process

The US Food and Drug Administration (FDA) has approved a new manufacturing process for SIMLANDI, Alvotech’s biosimilar to Humira, that more than doubles drug substance output per batch at the company’s facility in Reykjavik.

Global report – October 20, 2026

EMA panel backs Lilly’s oral GLP-1 Foundayo

The EMA’s Committee for Medicinal Products for Human Use (CHMP) has recommended EU approval of Eli Lilly’s Foundayo (orforglipron), a once-daily GLP-1 tablet for weight management and type 2 diabetes in adults. If approved, it will compete with Novo’s Wegovy pill in Europe.

Clinical Trials – October 20, 2026

Zealand’s autoimmune drug passes multiple-dose Phase 1

Zealand Pharma reports positive topline results from the multiple ascending dose part of its first-in-human Phase 1 trial of ZP9830, a Kv1.3 ion channel blocker being developed for autoimmune and inflammatory diseases.

Global report – October 20, 2026

Merck to acquire Silence Therapeutics for USD 1.3 billion

Germany’s Merck KGaA has agreed to acquire London-based Silence Therapeutics, adding a Phase III-ready siRNA therapy for the rare blood cancer polycythemia vera (PV) to its rare disease pipeline.

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Clinical Trials

Clinical Trials – October 20, 2026

ALK’s dust mite allergy tablet succeeds in Chinese Phase 3

Danish allergy company ALK-Abelló reports that its house dust mite tablet Acarizax met the primary objective of a Phase 3 trial in China, with efficacy in line with earlier trials after only 24–28 weeks of treatment. ALK and its partner GenSci plan to file for approval in China in the first half of 2027.

Clinical Trials – October 20, 2026

Zealand’s autoimmune drug passes multiple-dose Phase 1

Zealand Pharma reports positive topline results from the multiple ascending dose part of its first-in-human Phase 1 trial of ZP9830, a Kv1.3 ion channel blocker being developed for autoimmune and inflammatory diseases.

Clinical Trials – October 19, 2026

Evaxion’s cancer vaccine responses hold at three years

Danish Evaxion reports that all patients in its Phase 2 trial of the personalized cancer vaccine EVX-01 in advanced melanoma kept their clinical responses at the three-year follow-up, with no tumor progression observed.

Clinical Trials – October 19, 2026

BioInvent publishes first-in-human data for BI-1808

BioInvent has published results from the first clinical study of its anti-TNFR2 antibody BI-1808 in Clinical Cancer Research. In the Phase 1 dose escalation, no maximum tolerated dose was reached and all treatment-related side effects were grade 1 or 2.

Clinical Trials – October 19, 2026

Calluna completes dosing in Phase 2 IPF trial

Calluna Pharma has completed dosing in its Phase 2 AURORA study of CAL101 in idiopathic pulmonary fibrosis (IPF). Topline results are expected in the first quarter of 2027.

Clinical Trials – October 15, 2026

Modus Therapeutics pauses enrollment in sevuparin study

Modus Therapeutics has temporarily paused enrollment in Part 2 of its Phase IIa study of sevuparin in chronic kidney disease (CKD) with anemia after a serious adverse event in one patient. The company’s preliminary assessment is that the proof-of-concept readout will slip to the first quarter of 2027.

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NLS Insight

Business article – November 4, 2024

Navigating the Financial Landscape: Downsizing

Downsizing a company is one of the most difficult decisions a chief executive can make, after which comes the equally painful decision of when to do it.

Financial landscape – November 8, 2024

Navigating the Financial Landscape: Bankruptcy

Four months after XNK Therapeutics, located in Huddinge, Sweden, declared bankruptcy, the clinical-stage biotechnology company’s building and physical assets were sold and the lease agreement transferred to BioLamina. 

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