The patent forms the basis of a new vaccine platform that the company has developed in parallel with existing platforms.
The company has received a Notice of Allowance of its patent application “Fusion polypeptides comprising one or more inclusion body tags, methods and uses” by the US Patent Office.
A new vaccine platform
The new platform entails technology that allows the efficient production of disease-specific antigens in so-called protein bodies, nanosized protein particles that can be administered to the body as vaccines, states the company in a press release.
“The vaccine platform that will now receive patent approval in the US, we have worked on for several years in parallel with other technologies. We have used protein bodies as a comparison in many of our vaccine studies and thus gained proof-of-concept for the platform and different ways of delivering those vaccines to the body. It is an exciting technology that makes it possible to create vaccines that are very cost-effective and fast to produce. When developing vaccine candidates, we will now have the opportunity to both test variants based on protein bodies as well as our other platform based on bacterial vesicles. Hence, we will be able to choose the technology platform that is best suited for the unique disease we work with. It gives us a greater opportunity to create effective vaccines against diseases that still lack effective and cost-effective alternatives,” says Maria Alriksson, CEO of Abera Bioscience.
Applied for supplementary patents
The invention itself is a polypeptide tag that is expressed in fusion with an antigen and induces the accumulation of the fusion product in protein bodies in bacterial expression systems. It allows otherwise soluble or unstable antigens to be produced in protein body fashion. Abera has also applied for supplementary patents for the technology and intends to build a patent family around the innovation and its areas of use.
The application for patent in Europe has also been submitted but is still pending decision by the authorities.