
Drug development - November 19, 2024
Questions raised around myeloma treatments
In Sweden, recent debate and criticism regarding approved multiple myeloma treatments has shone the spotlight on IMiDs and their effects. NLS asked Fredrik Schjesvold, MD, PhD, founder and leader of Oslo Myeloma Center, Oslo University Hospital, about these drugs and the ongoing debate.

Clinical Trials - June 24, 2019
First patient enrolled in PCI Biotech study
The company has announced that the first patient has been enrolled in the fimaChem RELEASE study with registration intent in inoperable bile duct cancer patients. The pivotal RELEASE study has the potential of accelerated/conditional marketing approval as a first-line treatment given the rare disease status and high unmet medical need in this patient population, which […]

Clinical Trials - June 20, 2019
Alligator Bioscience submits clinical trial application
The company has submitted clinical trial authorization (CTA) application to initiate a Phase I study of its fully owned 4-1BB antibody ATOR-1017 for the treatment of metastasizing cancer. ATOR-1017 is an immunostimulatory IgG4 antibody that activates tumor-specific T cells and NK cells through the costimulatory receptor 4-1BB. T cells and NK cells have the capacity […]

Clinical Trials - June 18, 2019
New clinical data from BioInvent
The company has announced the publication of the first data from two parallel Phase l/lla clinical trials of its lead product candidate BI-1206 as single agent and/or in combination with rituximab, currently being conducting in the UK and the US/EU respectively. In the UK trial, 10 patients have received single agent therapy with up to […]

Clinical Trials - June 4, 2019
New data from Oncopeptides
Data from the company’s Phase 1/2 O-12-M1 clinical study of lead candidate melflufen demonstrate that melflufen may offer positive disease stabilization and favorable time to next treatment (TTNT) outcomes in heavily-pretreated patients with relapsed/refractory multiple myeloma (RRMM). Overall conclusions from the data presented include: Melflufen plus dexamethasone treatment results in disease stabilization in 76% of RRMM […]

Agreement - June 4, 2019
Xbrane enters term-sheet with STADA
The company has entered a non-binding term-sheet with STADA Arzneimittel for cooperation regarding sales and marketing of Spherotide for Europe, and furthermore, the company updates on its plans to take the product into a phase III study in endometriosis patients. Non-binding term-sheet with STADA The company´s non-binding term-sheet with STADA consists of an agreement to […]