Clinical Trials – October 7, 2026
Epcoritamab meets Phase III goal in frontline lymphoma
Genmab and AbbVie’s bispecific antibody epcoritamab, added to standard R-CHOP chemoimmunotherapy, significantly improved progression-free survival in the Phase III EPCORE DLBCL-2 trial in newly diagnosed diffuse large B-cell lymphoma (DLBCL). The companies say it is the first Phase III study of a bispecific antibody combination to show such a benefit in the frontline setting.