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NLS Selumetinib

Pharma Business - April 1, 2019

AstraZeneca’s Selumetinib granted Breakthrough Therapy Designation

AstraZeneca and MSD have announced that the US Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation (BTD) for the MEK 1/2 inhibitor and potential new medicine selumetinib. This designation is for the treatment of paediatric patients aged three years and older with neurofibromatosis type 1 (NF1) symptomatic and/or progressive, inoperable plexiform neurofibromas (PN), […]

Clinical Trials - August 16, 2016

AZ update Selumetinib trial

AstraZeneca has announced results from the Phase III SELECT-1 trial of the MEK 1/2 inhibitor, selumetinib, in combination with docetaxel chemotherapy as 2nd-line treatment in patients with KRAS mutation-positive (KRASm) locally-advanced or metastatic non-small cell lung cancer (NSCLC). The results showed that the trial did not meet its primary endpoint of progression-free survival (PFS), and selumetinib […]

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