Pyrogens, the Monocyte Activation Test and its challenges

Pyrogens in pharmaceutical products, biotherapeutics, or medical devices can trigger severe immune reactions from fever to sepsis.
April 20, 2025
The Monocyte Activation Test (MAT) is a reliable, animal-free method for pyrogen detection and is recognized by the European Pharmacopoeia. Learn how MAT works, the role of pyrogens in the body, and the challenges involved in applying this method.
Published: April 20, 2025