NLS COVID-19

Late Monday, the Data and Safety Monitoring Board (DSMB) notified NIAID, BARDA, and AstraZeneca that it was concerned by information released by AstraZeneca on initial data from its COVID-19 vaccine clinical trial. The DSMB expressed concern that AstraZeneca may have included outdated information from that trial, which may have provided an incomplete view of the […]

The AstraZeneca US Phase III trial of AZD1222 demonstrated vaccine efficacy of 79% at preventing symptomatic COVID-19 and 100% efficacy at preventing severe disease and hospitalization. This interim safety and efficacy analysis was based on 32,449 participants accruing 141 symptomatic cases of COVID-19, reports AstraZeneca in a press release. The trial had a 2:1 randomization […]

Finland has, as the last Nordic country, decided to temporarily suspend AstraZeneca’s COVID-19 vaccine. The country’s public health authority said two people developed blood clots after being vaccinated. As a result, vaccination will be suspended “until there is more information and a possible causality can be assessed”. The Nordic countries are now reviewing the EMA […]

The Medicines Health Regulatory Authority (MHRA) and European Medicines Agency (EMA) reaffirmed the benefits of COVID-19 Vaccine AstraZeneca continue to far outweigh the risks. The MHRA announced their review of the thromboembolic events in over 11 million people who received COVID-19 Vaccine AstraZeneca in the UK. The UK regulator confirmed that the benefits of the […]

CEPI, the Coalition for Epidemic Preparedness Innovations, has launched a USD 3.5 billion plan to dramatically reduce or even eliminate the future risk of pandemics and epidemics. CEPI’s five-year plan sets out initiatives to build a future world that is better equipped to deal with these devastating diseases. As part of the plan, CEPI announced […]

All Nordic countries except Finland have temporarily paused vaccination with COVID-19 Vaccine AstraZeneca, pending the EMA investigation. Events involving blood clots, some with unusual features such as low numbers of platelets, have occurred in a very small number of people who received the vaccine. EMA’s investigation has been continuing over the weekend, and analysis of […]