Collaboration - December 16, 2016
AstraZeneca, Lilly to develop treatment for Alzheimer’s
AstraZeneca and Eli Lilly and Company have signed a worldwide agreement to co-develop MEDI1814, an antibody selective for amyloid-beta 42 (Aβ42), which is currently in Phase I trials as a potential disease-modifying treatment for Alzheimer’s disease (AD). This agreement builds on the existing collaboration related to AZD3293, a BACE inhibitor in two pivotal Phase III […]
Biotech Business - December 14, 2016
FDA accepts AstraZeneca’s biologics license application
AstraZeneca and its global biologics research and development arm, MedImmune, announced that the US Food and Drug Administration (FDA) has accepted the first Biologics License Application (BLA) for durvalumab, a PD-L1 human monoclonal antibody (mAb), and granted priority review status with a Prescription Drug User Fee Act (PDUFA) set for the second quarter of 2017. […]
In a new job - December 1, 2016
New chief adviser for AZ’s genomics initiative
Professor David Goldstein will join AstraZeneca’s in the consultative role of Chief Adviser, Genomics to lead its integrated genomics initiative, which was announced in April. This 10-year initiative will focus on the discovery of new targets and biomarkers linked to molecular mechanisms of disease across AstraZeneca’s main therapy areas. Professor Goldstein will continue in his full-time […]
Clinical Trials - November 8, 2016
AstraZeneca head and neck cancer trials
Following the recent update on clinicaltrials.gov, AstraZeneca confirms that the US FDA has placed a partial clinical hold on the enrolment of new patients with head and neck squamous cell carcinoma (HNSCC) in clinical trials of durvalumab as monotherapy and in combination with tremelimumab or other potential medicines. All trials are continuing with existing patients. […]
Acquisition - October 4, 2016
AZ enters agreement with Cilag
AstraZeneca has entered into an agreement with Cilag GmbH International, an affiliate of Johnson & Johnson, for the divestment of the rights to Rhinocort Aqua outside the US. Rhinocort Aqua is a nasal spray indicated for allergic and non-allergic rhinitis (inflammation of the inside of the nose), and for the treatment of nasal polyps (swelling […]
Agreement - October 3, 2016
AstraZeneca in agreement with Allergan
AstraZeneca today announced that MedImmune, its global biologics research and development arm, has entered into a licensing agreement with Allergan plc for the global rights to MEDI2070. MEDI2070 is an IL-23 monoclonal antibody currently in a Phase IIb clinical trial for moderate-to-severe Crohn’s disease (a chronic inflammatory disease of the intestines) and is ready for […]
