NLS Karolinska Institutet

Researchers from Karolinska Institutet and the SciLifeLab Chemical Biology Consortium Sweden (CBCS) have identified a chemical compound, CBK77, that has the potential to inhibit protein recycling in cancer cells, subsequently leading to tumor cell death. CBK77 also turned out to have an unexpected advantage, it only affects cells that express the NQO1 enzyme, commonly upregulated […]

With the application of a novel 3D imaging technology, researchers at Karolinska Institutet have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease. The study, which is conducted in mice and human liver tissue, shows that the degeneration of nerves is correlated with the […]

Researchers at Karolinska Institutet has reported the results of a pilot project where drones were used to deliver defibrillators to real-life alerts of suspected cardiac arrest. The drones were dispatched in more than a fifth of the emergencies and arrived on target and ahead of the ambulance in most cases, states the researchers. The results […]

Researchers at Karolinska Institutet have developed a detailed molecular atlas of the fetal development of the brain. “Brain development is well described and the main cell types are known. What is new about our atlas is the high resolution and detail,” says Sten Linnarsson, head of research and professor at the Department of Medical Biochemistry […]

Researchers at Uppsala University and Karolinska Institutet have presented a new screening approach that focuses on the identification of virus-specific morphological changes in virus-infected cells. The new method focuses on identifying the changes (morphological profiles) that the virus induces on the infected cells by using a modified version of the Cell Painting protocol, an established […]

Researchers at Karolinska Institutet and the Public Health Agency of Sweden have shown that although babies born of test-positive mothers are more likely to be born early, extremely few were infected with COVID-19. The study, published in the journal JAMA, supports the Swedish recommendation not to separate mother and baby after delivery, states the researchers […]