NLS Karolinska Institutet

Children who develop inflammatory bowel disease (ulcerative colitis or Crohn’s disease) run a higher risk of cancer, both in childhood and later in life, reports a study from Karolinska Institutet published in The BMJ. Adulthood onset inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease have been associated with an increased risk of bowel cancer. […]

The dynamics among certain so-called G protein-coupled receptors, of vital importance for the function of cells in the body, are different than previously believed, reports researchers from Karolinska Institutet in the journal Nature Communications. The researchers has shown that a specific G protein-coupled receptor named Frizzled 6 (FZD6) can switch between acting in pairs and as […]

Researchers at Karolinska Institutet have obtained the first 3D snapshots of a sperm protein attached to a complementary egg coat protein at the beginning of fertilisation.

Scientists at Karolinska Institutet report that cancer cells and normal cells use different ‘gene switches’ in order to regulate the expression of genes that control growth. In mice, the removal of a large regulatory region linked to different types of cancer caused a dramatic resistance to tumour formation, but did not affect normal cell growth. […]

Researchers at Karolinska Institutet has shown how blood vessels can normally change their size to create a functional circulatory system and how vascular malformation during disease can occur. In the study, published in Nature Cell Biology , the researchers managed to treat vascular malformation in mice, a discovery of potential significance to numerous vascular diseases. […]

Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia. The drugs currently available for schizophrenia are designed to alleviate the symptoms, but are only partly successful, as only 20 per cent of the patients become symptom-free.  The Karolinska Schizophrenia Project (KaSP) […]