NLS Research

A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some ‘master’ regulatory proteins can activate regions of the genome that are normally inactive due to epigenetic changes. Their findings contribute to a better understanding […]

Researchers at Karolinska Institutet has shown how blood vessels can normally change their size to create a functional circulatory system and how vascular malformation during disease can occur. In the study, published in Nature Cell Biology , the researchers managed to treat vascular malformation in mice, a discovery of potential significance to numerous vascular diseases. […]

The new Stockholm3 test for prostate cancer diagnosis, gets assistance from EIT Health for a faster introduction in Europe. In a first step the test will be clinically validated in Germany, the Netherlands and Belgium. The Stockholm3 test was developed by researchers at Karolinska Institutet. EIT Health, supported by the EU body European Innovation and […]

Researchers have identified cell surface markers specific for the very earliest stem cells in the human embryo. These cells are thought to possess great potential for replacing damaged tissue but until now have been difficult to distinguish from classical embryonic stem cells. Fredrik Lanner’s research team at Karolinska Institutet and their colleagues in Peter Rugg-Gunn’s […]

Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia. The drugs currently available for schizophrenia are designed to alleviate the symptoms, but are only partly successful, as only 20 per cent of the patients become symptom-free.  The Karolinska Schizophrenia Project (KaSP) […]

Researchers have been able to demonstrate the hereditary nature of certain forms of tinnitus, and bilateral tinnitus has been shown to depend on genetic factors, particularly in men. The twin study, which is published in the journal Genetics in Medicine , was conducted by researchers at Karolinska Institutet together with colleagues from the European research […]