Science article - August 10, 2016
Making a malaria protein to kill cancer cells
While developing a malaria vaccine for pregnant women, scientists at the University of Copenhagen Department of Immunology and Microbiology found an unique molecule. Cancer researchers had been searching for something like it for decades. The molecule, explains Professor Ali Salanti, leader of the research group, is a certain chondroitin sulfate (CS), a modified carbohydrate. The […]
Science article - August 1, 2016
Older and wiser about cancer
The population of Northern Europe is aging and this means an increase in cancer diagnoses. Is this good news or bad? People over age 65 have a ten-fold higher risk of cancer than people under age 65. But cancer in older people is more complex than that number. For example, some leukemias are more aggressive […]
Science article - April 6, 2016
Finding global biodiversity in your town
Zoos are a research treasure, a Cell paper shows. Humans and chimpanzees have nearly identical genes. But we use those genes differently, in part because of changes in gene-regulating regions such as promoters, which are close to genes they control, and enhancers, which can be hundreds of bases away. A Cell paper from UK and […]
Science article - January 2, 2016
Catching an enzyme in the act of catalysis
Previously invisible enzyme structure revealed with protein engineering and NMR. Enzymes are dynamic proteins. They shift, bend and flex as they catalyze a reaction. X-ray crystallography shows their stable forms but not their fleeting, intermediate conformations. To design enzymes for applications such as retrieving high-value molecules from cellulose, we need to understand their transitional states. […]
Science article - November 16, 2015
The epigenetic effects of exercise
Karolinska Institute researchers find that training alters DNA. Why is exercise healthy? Maybe because it changes DNA and affects expression of genes in physiology and metabolism, according to new research from the Karolinska Institute. The study made the news, in part because of a creative design. Exercise changed DNA methylation and gene expression In the […]
Science article - March 19, 2013
The quest for funding
Applying for grants is part of the everyday life of Swedish researchers. But the task can be a time consuming and difficult project when the competition is tough.