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Researchers at FIMM have developed a computational approach that can automatically identify various cell types based on single-cell RNA-sequencing data. The method has a huge potential for unbiased profiling of mixtures of cells, both for large-scale projects and samples derived from a single patient, states the researchers. It is not yet known how many different […]

Asgard Therapeutics has reached an important milestone in the development of its lead gene therapy product, TrojanDC, a cancer immunotherapy based in cell reprogramming. Through research, the founders of the company have increased the efficiency of their reprogramming methodology approximately 190-fold, allowing efficient conversion of multiple human cell-types into dendritic cells (DCs) able to set […]

A new study from Karolinska Institutet shows how certain RNA molecules control the repair of damaged DNA in cancer cells, a discovery that could eventually give rise to better cancer treatments. New research demonstrates that RNA molecules have a much broader function than previously thought and can play a key role in the development of […]

A functional precision medicine study conducted in Finland demonstrates that treatment selection based on results from drug sensitivity testing of patients’ cells can be clinically useful in patients with aggressive hematological cancers. Clinicians, researchers and technology experts from the Institute for Molecular Medicine Finland FIMM at the University of Helsinki and Helsinki University Hospital Comprehensive […]

Swedish researchers and doctors have successfully treated a child with neuroblastoma by using a tailored precision medicine approach. “Combining genetic mapping and biological understanding with a new targeted treatment is precision medicine made real, which can make a difference and cure more children who have cancer,” says co-last author Per Kogner (Karolinska Institutet/Astrid Lindgren Children’s […]

An international research team have mapped how the signalling molecules caused by exercise are releases by different organs in mice following exercise at different times of the day. Their atlas of exercise metabolism, published in the journal Cell Metabolism, may in the long term contribute to more effective exercise therapies that are timed to the […]