NLS Research

A new study from Karolinska Institutet and the University of Helsinki show that therapeutic use of gene editing with the CRISPR-Cas9 technique may inadvertently increase the risk of cancer. Two independent articles published in the journal Nature Medicine report that therapeutic application of the genome-editing tool may increase the risk of cancer. In one of the studies, […]

A network for the promotion of research and education in microfluidics was recently launched at a conference at SciLifeLab. Microfluidics is a research area that deals with fluids on the micrometer scale, the scale of human cells. Microfluidics is a key enabling technology for genomics and point-of-care (POC) diagnostics and is finding uses throughout the […]

On May 28th international scientists and experts within outcomes research and patient centred healthcare gathered at the Karolinska Institute to discuss patient-driven development of pharmaceuticals, Swedish quality registers and their role in research, as well as how the patient best could be involved to optimize healthcare. “Sweden is at the forefront when it comes to […]

High activity in a relatively poorly studied group of brain cells can be linked to aggressive behaviour in mice, a new study from Karolinska Institutet in Sweden shows. Using optogenetic techniques, the researchers were able to control aggression in mice by stimulating or inhibiting these cells. The results, which are published in the scientific journal Nature […]

Scientists at Karolinska Institutet in Sweden and University of North Carolina, USA, have identified the cell types underlying schizophrenia in a new study published in Nature Genetics. Genetic studies have linked hundreds of genes to schizophrenia, each contributing a small part to the risk of developing the disease. The great abundance of identified genes have made […]

Researchers at Karolinska Institutet have developed a new disease model for neurodegenerative diseases such as ALS and MS that can be used to develop new immunotherapies. In a healthy brain, microglia are involved in interneuronal communication and the renewal of myelin, the insulating sheaths enveloping axons of nerve cells that enable the transmission of nerve […]