NLS Research

Results of the Prostate Cancer DREAM Challenge published in the clinical oncology journal Lancet Oncology demonstrate the benefits of sharing clinical trial data. The winning prediction model was developed by a team headed by FIMM Group Leader Tero Aittokallio. Overall, this collaborative scientific effort led to novel insights and improvements in cancer treatment and management. In 2015, professor Aittokallio’s team excelled in Sage […]

A discovery by Lund University scientists could advance transplants. Why do fetuses have bile? This compound usually goes from the gall bladder to the intestines to help digest fats. “It seems strange,” says Assistant Professor Kenichi Miharada at Lund University Division of Molecular Medicine and Gene Therapy, “because fetuses don’t eat food, so they don’t […]

Endurance training changes the activity of thousands of genes and give rise to a multitude of altered DNA-copies, RNA, researchers from Karolinska Institutet report. The study, which also nuances the concept of muscle memory, is published in the journal  PLOS Genetics . Regular endurance training is very beneficial to health and wellbeing, and can be […]

In a study, researchers from Karolinska Institutet has been able to show the immunological effects of statins, and present a new hypothesis on why satins are effective at preventing heart attacks. Atherosclerosis can lead to a number of serious medical conditions, such as heart attack, stroke and intermittent claudication. These and other cardiovascular diseases are […]

Researchers at Karolinska Institutet and the Feinstein Institute for Medical Research have discovered that the human immune system has a hitherto unknown role – blood pressure regulation. Collaborating with colleagues from Canada, the researchers have found that a special kind of immune cell called acetylcholine-producing lymphocytes can regulate blood pressure in laboratory mice. The study, […]

Thousands of genes and their interactions across tissues mediating cardiometabolic diseases have been identified. The research, published in Science , is a result of a joint collaboration between the Icahn School of Medicine at Mount Sinai, Tartu University Hospital in Estonia, Karolinska Institutet and Science for Life Laboratory (SciLifeLab) in Sweden, and AstraZeneca. The identified […]