NLS Research

FIMM researchers have demonstrated that a previously approved drug called idelalisib is a promising treatment option for leukemia patients with the t(1;19) translocation. Fusion genes are hybrids formed from two separate genes by structural genomic rearrangements. They play an important role in tumorigenesis, and they are often found in leukemias and other types of cancer. […]

Researchers at the University of Copenhagen have studied gatekeepers of cell membranes one at a time with revolutionary nanotechnology. They found that these gatekeepers can be manipulated to work longer hours by turning on a molecular switch. In order to let useful molecules go through the membrane, cells use gatekeeper molecules called transporters. The findings […]

An international research consortium has identified almost 30 new genetic risk factors for common migraine. Many of these risk variants localize inside or close to genes that regulate the vascular system. The results provide further support for the theory that an abnormal function of the blood vessels of the brain is an important component in […]

Oligodendrocytes, a type of brain cell that plays a crucial role in diseases such as multiple sclerosis, are more diverse than have previously been thought, according to a new study by researchers at Karolinska Institutet in Sweden. The findings, published in the journal Science , will help increase our understanding of diseases in which these […]

In a new study, researchers from the Karolinska Institutet in Sweden and from the Institute of Health and Medical Research (INSERM) in France have identified epigenomic alterations that are associated with inflammation and type 2 diabetes. The findings, which are published in the journal Nature Medicine , help to explain how alterations of the epigenome […]

Men with blood cells that do not carry the Y chromosome are at greater risk of being diagnosed with Alzheimer’s disease. This is in addition to an increased risk of death from other causes, including many cancers. These new findings by researchers at Uppsala University could lead to a simple test to identify those at […]