Uncategorized - May 24, 2016
Breakthrough findings from Oslo researchers
Researchers Erlend Strønen, Johanna Olweus and the Immunotherapy Jebsen Center in Oslo’s work on a breakthrough methodological development in generating broad and tumour-specific T-cell immune responses has been published in the journal Science. The researchers from the Netherlands Cancer Institute and University of Oslo/Oslo University Hospital show that even if one’s own immune cells cannot recognize […]
Uncategorized - April 26, 2016
Strongest single gene conclusively implicated in schizophrenia
An international consortium of researchers has discovered conclusive evidence for the involvement of a gene called SETD1A in schizophrenia. Damaging changes to this gene, which occur rarely, increase the risk of schizophrenia 35-fold and also increase risk for a wide range of neurodevelopmental disorders. The consortium led by a team at the Wellcome Trust Sanger […]
Uncategorized - April 15, 2016
Principle for brain-controlled hormone secretion
A new study from Karolinska Institutet in rats, published in the journal Cell Reports, shows how dopamine can regulate itself and provides new knowledge about how the side effects arise. The concentration of the hormone prolactin in the blood is controlled by dopamine. However, the system can be thrown off balance by certain drugs, especially […]
Uncategorized - April 11, 2016
A new version of the human protein atlas
Today, the Human Protein Atlas consortium launched version 15 of the database including extensive transcriptomics data and a new display view to allow comparisons of human tissue profiles on both the RNA and protein level. The launch is accompanied with an article in Molecular Systems Biology describing transcriptome resources with a focus on the comparison […]
Uncategorized - March 1, 2016
Novel molecular processes controlling key genes in prostate cancer uncovered
Researchers Karolinska Institutet in Sweden and the University of Oulu in Finland have elucidated gene regulatory mechanisms that can explain how known genetic variants influence prostate cancer risk. The findings, published in the journal Nature Genetics , reveal widespread deregulation of androgen receptor function, a key player in prostate cancer. The vast majority of the […]
Uncategorized - February 13, 2016
New subgroups of ILC immune cells discovered
A relatively newly discovered group of immune cells known as ILCs have been examined in detail in a new study published in the journal Nature Immunology. By analysing the gene expression in individual tonsil cells, scientists at Karolinska Institutet in Sweden have found three previously unknown subgroups of ILCs, and revealed more about how these […]
