NLS Karolinska Institutet

Researchers at Karolinska Institutet in Sweden have for the first time identified a gene driving the development of pernicious adipose tissue in humans. The findings imply, which are published in the scientific journal Cell Metabolism, that the gene may constitute a risk factor promoting the development of insulin resistance and type 2 diabetes. Adipose tissue […]

The origin of each type of cancer is a small group of stem cells that drives the disease development. The gene mutations driving cancer have been tracked for the first time in patients back to a distinct set of cells at the root of cancer – cancer stem cells. The international research team, led by […]

Construction group Skanska has signed a deal with Akademiska Hus to build a new laboratory for Karolinska Institutet. The order regards the building of a ninth floor laboratory for medical research at the Karolinska Institute Campus in Solna, north of Stockholm, and will contain approximately a total of 17 000 squaremeteter work space. The laboratory […]

There is once again hope of a new anti-inflammatory drug based on the principal of blocking LTA4 hydrolase. There have been great expectations regarding the production of a drug to block the enzyme LTA4 hydrolase, which plays a key role in the body’s inflammatory response. However, in clinical trials, such molecules have proven to be […]

New study indicates that the environment has larger effects on genes than previously assumed. According to recent research, in which scientists from Karolinska Institutet have participated, show that what we eat can have effects on the genetic material and leaves traces in generations to come.  The study, published in BMC Genetics, has investigated whether large fluctuations in […]

In a study published in Nature Communications, researchers at Uppsala University and Karolinska Institutet present a new drug candidate which selectively kills dormant cells within a cancer tumour through starvation. These tumour cells, which are found in less oxygenated parts of solid tumours, are resistant to conventional treatments. In solid tumours larger than a few millimetres, […]