Uncategorized - March 14, 2017
Large-scale Schizophrenia project provides new clues
Researchers at Karolinska Institutet collaborating in the large-scale Karolinska Schizophrenia Project are taking an integrative approach to unravel the disease mechanisms of schizophrenia. The drugs currently available for schizophrenia are designed to alleviate the symptoms, but are only partly successful, as only 20 per cent of the patients become symptom-free. The Karolinska Schizophrenia Project (KaSP) […]
Uncategorized - February 23, 2017
Schizophrenia linked to mother’s low weight during pregnancy
Children born to mothers who gained too little weight during pregnancy were at increased risk for schizophrenia and other non-affective psychoses later in life, according to new epidemiological research from Karolinska Institutet. The findings, published in the journal JAMA Psychiatry , confirm the results of several important historical studies that showed a link between exposure […]
Uncategorized - April 26, 2016
Strongest single gene conclusively implicated in schizophrenia
An international consortium of researchers has discovered conclusive evidence for the involvement of a gene called SETD1A in schizophrenia. Damaging changes to this gene, which occur rarely, increase the risk of schizophrenia 35-fold and also increase risk for a wide range of neurodevelopmental disorders. The consortium led by a team at the Wellcome Trust Sanger […]
Drug Development Pharma - July 16, 2015
Priority Review for Janssen Drug
The US Food and Drug Administration (FDA) has approved under priority review Janssen Pharmaceuticals’ New Drug Application (NDA) for the three-month long-acting atypical antipsychotic Invega Trinza. Priority review is a designation for drugs that, if approved, would offer significant improvement in the treatment of serious conditions. In a long-term maintenance trial, 93 percent of patients […]
Iceland - June 21, 2015
Study Finds Creativity, Mental Disorder Link
An international team of scientists has found a genetic link between creativity and the development of two psychiatric disorders: schizophrenia and bipolar disorder, according to a recent study published in Nature Neuroscience. The scientists report that people with these psychiatric disorders share common gene variants with otherwise healthy, creative people, notes an article in ScienceNordic. […]
Clinical Trials - April 2, 2015
Antipsychotic Trial Results Published
Results from a multicenter study evaluating the effects of the investigational compound brexpiprazole as monotherapy in adult patients with schizophrenia recently were published online by the American Journal of Psychiatry. Brexpiprazole is an investigational psychotropic compound discovered by Otsuka Pharmaceutical, Co., Ltd. and under co-development with Lundbeck. The study, “Efficacy and Safety of Brexpiprazole for […]
