Nordic Life Science asked the newly formed company NordicRWE about the potential of Real-World Evidence in drug development and how we can better enable Nordic health data to be transformative
Nordic Life Science
In focus
Swedish researchers and doctors have successfully treated a child with neuroblastoma by using a tailored precision medicine approach. “Combining genetic mapping and biological understanding with a new targeted treatment is
Scientists at deCODE genetics have demonstrated how measuring the levels of a large number of proteins in plasma at a population scale when combined with data on sequence diversity and
An international research team have mapped how the signalling molecules caused by exercise are releases by different organs in mice following exercise at different times of the day. Their atlas
A new invention to measure the size of protein aggregates (proteins that clump together) can determine very precisely whether a person has systemic lupus erythematosus (SLE) or not and the
Researchers from Karolinska Institutet and the SciLifeLab Chemical Biology Consortium Sweden (CBCS) have identified a chemical compound, CBK77, that has the potential to inhibit protein recycling in cancer cells, subsequently
Researchers at Karolinska Institutet, Umeå University, and the University of Bonn have identified a new group of molecules that have an antibacterial effect against many antibiotic-resistant bacteria. Since the properties
The human brain, consisting of approximately 86 billion neurons connected by around 100 trillion synapses (Herculano-Houzel, 2009), is in many aspects still a mystery. Many questions remain unsolved, from understanding
Scientists at Icelandic deCODE genetics have found a new biomarker for osteoarthritis, that outperforms previously reported biomarkers and is an independent predictor of disease. In a study published in the
Researchers at the University of Helsinki are growing a human-derived mini-brain from stem cells, containing all of the most important cell types of the human brain. The mini-brain can be
Scientists have identified 15 novel biomarkers that are linked to late-onset dementias. These biomarkers are proteins, which predict cognitive decline and subsequent increased risk of dementia already 20 years before
The Nobel Prize in Chemistry 2021
The Nobel Prize in Chemistry 2021 shed light on a simple, sustainable and smart molecular building tool that has had a great impact on pharmaceutical production. The Royal Swedish Academy
Sometimes a simple event can have far-reaching consequences, as in the case of Princeton University professor Dr. David MacMillan, when a leaky roof led to an award-filled career in chemistry.
One of the best things with being a scientist, according to Nobel Laureate Benjamin List, is that you discover things that nobody else has seen before – and, following his
NLS Insight
The 2019 Nobel Prize in Physiology or Medicine was awarded to William G. Kaelin Jr., Sir Peter J. Ratcliffe and Gregg L. Semenza for revealing the mechanism of one of
Piece by piece the Nobel Laureates laid the puzzle in understanding and determining the hepatitis C virus, a discovery that has saved millions of lives. The Nobel Prize in Physiology
The discovery of CRISPR/Cas9 genetic scissors has revolutionized a lot of research areas, not least within life sciences, and the technology is bringing hope for new cancer therapies and the
The Nobel Prize in Chemistry 2019 recognizes the creation of a rechargeable world that paved the way for pacemakers. The Nobel Prize in Chemistry 2019 was awarded jointly to John
Swedish scientist Gabriella Lundkvist explains how the cellular mechanisms of the circadian clock may be altered in psychiatric disease and how she has been able to watch the molecular clock
Careers
Anna-Leena Saarela is an expert in pharmacovigilance and she sees it as a privilege to work in the front line of this fast developing environment for the benefit of patient
Nobel Laureates
With a passion for medical research sparked at the age of 17, Michael Houghton has been able to prevent millions of people from suffering from hepatitis C, and he expects
A loss for the world’s sea urchins turned into a win for virology research. When Dr. Charles M. Rice, PhD, entered a doctoral program at the California Institute of Technology,
Nobel Laureate Harvey J. Alter has focused his scientific career on investigating the causes of transfusion transmitted hepatitis. Doing research and working closely with small groups of patients turned out
It is International Women’s Day and and we like to highlight some of the many inspiring women in life science we have had the opportunity to meet and interview. Frances
Sir Peter J. Ratcliffe defined a system involved in inflammation, metabolism, cancer, and more. On 7 October 2019, Sir Peter J. Ratcliffe was having a typical scientist’s day, writing a
Since nothing is more basic to life than oxygen, Dr. Gregg Semenza, MD, PhD, found it logical to want to unravel some of the complexities of how cells monitor and
William Kaelin feels he has been fortunate in his scientific career. His contributions have had a great impact, not least within cancer treatment, and for future generations he emphasizes the
Phage display is used to discover antibody therapies including Humira for rheumatoid arthritis, Portrazza for cancer, and Benlysta for lupus. The 2018 Chemistry Nobel Prize honored three scientists for evolving,
Winning the Nobel Prize in chemistry generates a flood of phone calls, emails and invitations, which really was not a surprise to Sir. Fraser Stoddart, PhD, one of a trio
As a child, Jean-Pierre Sauvage, PhD, moved often, due to his father’s career in the French army. Postings included North Africa and the U.S. Midwest. But despite the disruptions to
Bernard L. Feringa is pioneer in the field of molecular engines and he strives to inspire his students, stimulate their creativity and help them appreciate the beauty of nature. When
The 2016 Nobel Prize in Physiology or Medicine highlights a process that is integral to aging, cancer, and infectious disease, but has not been well known outside of cell biology.
For Nobel Prize Winner Paul Modrich science is about using inner creativity and seeing an idea transform step by step into new exciting discoveries. A curiosity and love for problem-solving
In 1969 Professor Youyou Tu was recruited to a secret medical research project, it would change hers and millions of other people’s lives forever. Professor Youyou Tu from China shared
Japanese Professor Satoshi Ōmura is widely recognized for his discovery, development, biosynthesis and manipulation of useful chemicals derived from naturally-occurring microorganisms. It is also for this valuable work – described
Aziz Sancar’s love for the world of chemistry led him to the other side of the Atlantic and to the Nobel Prize winning breakthroughs of mapping DNA repair. At 5
Professor Campbell has always been fascinated by parasites, he even paints their mouthparts as if they were flowers in a vase. He has also spent most of his life figuring
According to Professor Tomas Lindahl successful scientists have a lot in common with successful musicians. It takes dedication and many hours of practicing. His passion and hard work led him
For William E. Moerner, research is not something done in isolation; it also is a valuable teaching tool. “Teaching young people to do research—that is a huge fraction of my
Despite earning multiple degrees in physics and all his years doing research, Nobel Prize winner Dr. Eric Betzig sees himself foremost as…a tool builder. “One of the greatest things about
Stefan W. Hell, PhD, likes to get down to the fundamentals. As an undergraduate, he disliked hearing professors say, “If you do the maths, you’ll know why this is so.”
Jack W Szostak was honored with the Nobel Prize in Physiology or Medicine 2009. Jack W Szostak, Elizabeth H. Blackburn and Carol Greider received the Medicine Nobel prize 2009 for
The 2009 Nobel Prize in Chemistry was awarded to three scientists for mapping the ribosome at the atomic level. The pioneering work was performed by the Israeli crystallographer Ada Yonath,
Profiles in Science
Massachusetts Institute of Technology (MIT) in the US has produced more than its share of engineers and computer scientists, but unlike many of his peers, alumnus Dr. Robert Langer, ScD,
An academic and an entrepreneur, Dr. Sara Mangsbo, PhD, has found a way to integrate her skills and interests so that they complement and augment her passions. The Chief Innovation
In an interview in Nordic Life Science, the Head of AstraZeneca’s Oncology Business unit, shared his insights on current drug development within oncology and how we can create faster access
After ten years of diabetes research and development at Novo Nordisk, Dorte X. Gram took her findings and work further to start something on her own. As founder and CEO
Sirpa Jalkanen is a professor in the Academy of Finland, board member of Orion, and cofounder of BioTie Therapies and Faron Pharmaceuticals. BioTie Therapies and Faron Pharmaceuticals develop drugs for
Academia and business don’t always mix, but Agnete B. Fredriksen of Norway has found the formula. While doing research for her doctorate degrees at the University of Oslo, Fredriksen and